Benefits
Automated DNA quantification of ALL samples simultaneously
Generates clean fragments of a precise size range of interest
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Time and reagent saving
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Fast run time leading to decreased turnaround time
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Accurate DNA quantification
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Integration with automated library preparation platform
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Enriches fetal fraction by two-fold
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Allows for high-multiplexing in the future
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Allows for more consistent analysis, further reducing failure rate
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Reduce or eliminate the hassle and wasted time & expense of sequencing off-target fragments
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Lower pool concentrations needed (from only 100pM), decreasing failure rate


The Yourgene QS250, supplied by Yourgene Health performs:
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Fragment length analysis
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Accurate Library quantification
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Enrichment of DNA of interest
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All with a single piece of equipment
IONA® Nx, is a screening test that performs:
1. Whole genome analysis to measure the likelihood that a pregnant woman is carrying a fetus with:
Most common trisomies
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Trisomy 21 (Down’ Syndrome)
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Trisomy 18 (Edwards’ Syndrome)
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Trisomy 13 (Patau’s Syndrome)
Autosomal Aneuploidies (AAs)
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Additional trisomy across the whole-genome
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All monosomy across the whole-genome
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Sex Chromosome Aneuploidies (SCAs)
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45,X (Turner Syndrome)
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47,XXX (Trisomy X)
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47,XXY (Klinefelter’s Syndrome)
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47,XYY (Jacob’s Syndrome)
2. Fetal Sex Determination
Key Features of the IONA® Nx NIPT Workflow
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Advanced proprietary reagents and software technologies
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Simple process with minimum instrumentation capital expenditure, suppliers and contract services
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Designed to offer flexibility (automated or manual) and scalability to suit varying customer needs