Features & Benefits
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Detects down to 0.05% fraction of chimerism – Allows earlier detection of graft rejection and disease relapse
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Accurate and precise measurement over the entire dynamic range from 0.05 – 100% chimerism using a single method – One measurement method regardless of the level of mixed chimerism
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A single workflow for both screening and monitoring – Eliminates the need for sample-specific primers and patient-specific marker tracking
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Single-tube NGS method – One universal reagent mix for all patients helps reduce reagent wastage and the need for keeping multiple reagents in stock
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User-friendly, designed-for-purpose software with automatic marker identification and chimerism calculation – Speeds up results analysis and eliminates manual data input
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Screening samples are sequenced only once – Saves time and increases lab productivity
Devyser Chimerism NGS
Devyser Chimerism NGS utilizes NGS technology for very early detection of graft rejection and disease relapse in hematopoietic stem cell transplanted patients.
For further information on the Devyser Chimerism NGS Kit, click here.
To download the Devyser Chimerism NGS Kit handbook, click here.
Features & Benefits
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Single-tube NGS assay for simultaneous comprehensive analysis of the HBA and the HBB gene clusters
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Full gene sequencing of HBA1, HBA2 and HBB genes enables detection of all SNVs
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Robust CNV detection with two combined strategies for CNV detection: Direct detection of 17 CNVs Coverage based detection of CNVs in both the HBA and the HBB gene clusters
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Built in rapid sample mix-up control through sex chromosome markers
Features & Benefits
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Detect all mutations in BRCA1 and BRCA2
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One tube per sample means no need for sample splitting
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Reduce hands-on time from days to under 45 minutes
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One kit for both germline and somatic mutations
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Choice of several validated software options, including CNV analysis
Devyser BRCA NGS
Devyser BRCA NGS utilizes NGS technology and proprietary multiplex PCR primer chemistry to provides full and uniform coverage of BRCA1 and BRCA2, covering all exons and exon/intron junctions. The kit uses overlapping primer design to ascertain superior INDEL coverage and downstream CNV analysis. It can be used to detect both germline and somatic mutations.
For further information on the Devyser BRCA NGS Kit, click here.
To download the Devyser BRCA NGS Kit handbook, click here.
Devyser Thalassemia NGS
With the Devyser Thalassemia kit you can detect all mutations in HBA1, HBA2 and HBB using a single, one-tube NGS assay. The assay detects single nucleotide polymorphisms (SNVs), indels and CNVs. The extremely simple procedure makes it an excellent choice for any lab, whether you are running advanced second level genetic testing or large scale mutation screening. The fast, simple and robust NGS workflow replaces complex multi-step protocols and eliminates the need for maintaining multiple thalassemia assays in your lab.
For further information on the Devyser Thalassemia NGS Kit, click here.
To download the Devyser Thalassemia NGS Kit handbook, click here.
Features & Benefits
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Detect mutations in genes with a recognised connection to the development of breast and ovarian cancers
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Can be used as a follow-up after negative BRCA testing, or combined with Devyser BRCA for analysis of 14 genes in total
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End-to-end CE-IVD solution including NGS library preparation and a customised data interpretation software
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Targeted sequencing with high uniformity reduces sequencing costs by maximising sample capacity on every NGS flowcell
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User friendly workflow with 45 mins hands-on time and a total laboratory process time of five hours from DNA to sequencing
Devyser HBOC NGS
Devyser HBOC NGS utilizes NGS technology for targeted sequencing of 12 genes relevant for hereditary breast and ovarian cancers (HBOC).
It can be used as a follow-up after negative BRCA testing, or combined with Devyser BRCA NGS Kit for analysis of 14 genes in total
For further information on the Devyser HBOC NGS Kit, click here.
To download the Devyser HBOC NGS Kit handbook, click here.