Features & Benefits
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One tube per sample means no need for sample splitting
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Reduce hands-on time from days to under 45 minutes
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Direct detection of CNVs
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Detect all mutations in the coding regions of the CFTR gene
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Determination of poly-T and TG repeats
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Choice of several validated software options, including CNV analysis
Devyser CFTR NGS
Devyser CFTR NGS is a single tube NGS library prep kit for targeted, complete CFTR gene sequencing.
For further information on the Devyser CFTR NGS Kit, click here.
To download the Devyser CFT NGS Kit handbook, click here.
Features & Benefits
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Detects 68 CFTR mutations, the polyT tract and associated number of TG repeats
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Only two mixes required to detect both wild-type and mutation status
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Mutation mix also includes the wild-type allele for the F508 deletion to check its zygosity
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Cross-mix ID markers to detect sample mix-up
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Fragment-analysis based
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CE-IVD
Devyser CFTR 68
Devyser CFTR 68 is a fragment analysis-based kit that enables fast and reliable detection of cystic fibrosis-causing mutations, using a multi-ethic panel of 68 CFTR mutations that achieves high detection rates while keeping the workload and costs to a minimum.
For further information on the Devyser CFTR 68 NGS Kit, click here.
To download the Devyser CFTR NGS Kit handbook, click here.
Features & Benefits
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Detects polythymidine variants (5T/7T/9T) within intron 9 (IVS8) of the CFTR
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In case of a 5T variant, also detects the TG repeat number
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Runs on all Thermofisher/ABI capillary electrophoresis instruments * View full list of mutations detected in product details
Devyser CFTR Core
Allele-specific genotyping of a panel of normal and mutated alleles in the CFTR gene common in the European population.
For further information on the Devyser CFTR Core Kit, click here.
To download the Devyser CFTR Core Kit handbook, click here.
Detection of the following CFTR mutations
711+5A, 1898+3G, 2184delA, 4016insT, 4382delA, M1V, P5L, Q39X, D110E, D110H, G178R, R352Q, S549R(A>C), Q552X, D579G, E585X, R1066H, D1152H, R1158X, G1244E, CFTRdele1, CFTRdele2, CFTRdele2ins182, CFTRdele14b-17b, CFTRdele17a-18, CFTRdele22,23, CFTRdele22-24, 852del22, 1259insA, G1349D, c.1584+18672A>G and corresponding wild type alleles.
Devyser CFTR Italia
A Cystic fibrosis diagnostic test specifically for patients with Italian ancestry. Enables detection of 31 mutations specifically found in the Italian population with parallel detection of the corresponding normal alleles. Devyser CFTR Italia also includes analysis of cross-mix ID markers for sample identity confirmation between different Devyser CFTR products.
For further information on the Devyser CFTR Italia Kit, click here.
To download the Devyser CFTR Italia Kit handbook, click here.
Features & Benefits
Detects the following mutations
Q1100P, M1101K, 1812-1G>A, 1609delCA, 1898+3A>G, R709X, V232D, S549R (T>G), L206W, P205S, H199Y, 712-1G>T, 2869insG, 1811+1,6kbA>G, Q890X and corresponding wild type alleles.
Devyser CFTR Iberia
A Cystic fibrosis diagnostic test specifically for patients with Italian ancestry. Enables detection of 15 mutations specifically found in patients of Spanish and Portuguese ancestry, with parallel detection of the corresponding normal alleles. Devyser CFTR Iberia also includes analysis of cross-mix ID markers for sample identity confirmation between different Devyser CFTR products.
For further information on the Devyser CFTR Iberia Kit, click here.
To download the Devyser CFTR Iberia Kit handbook, click here.
Features & Benefits
Detects the following CFTR mutations
E60X, P67L, Q98X, 621+2T>C, L218X, 1154insTC, 1161delC, 1525-1G>A, Q493X, V520F, S549N, Y569D, S589N, 1898+5G>T, D1152H, R1158X, R1283M and corresponding wild type alleles.
Devyser CFTR UK
A Cystic fibrosis diagnostic test specifically for the UK population, including common Celtic, Chinese and Pakistani mutations. Enables detection of 17 mutations specifically found in the Italian population with parallell detection of the corresponding normal alleles. Devyser CFTR UK also includes analysis of cross-mix ID markers for sample identity confirmation between different Devyser CFTR products.
For further information on the Devyser CFTR UK Kit, click here.
To download the Devyser CFTR UK Kit handbook, click here.